The DEAD-Box Protein DP103 (Ddx20 or Gemin-3) Represses Orphan Nuclear Receptor Activity via SUMO Modification

Structural analysis of nuclear receptor subfamily V orphan nuclear receptors suggests that ligand-independent mechanisms must regulate this subclass of receptors. Here, we report that steroidogenic factor 1 (SF-1) and liver receptor homolog 1 are repressed via posttranslational SUMO modification at...

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Bibliografiske detaljer
Main Authors: Lee, Martin B., Lebedeva, Lioudmila A., Suzawa, Miyuki, Wadekar, Subhagya A., Desclozeaux, Marion, Ingraham, Holly A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549377/
https://ncbi.nlm.nih.gov/pubmed/15713642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1879-1890.2005
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