Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target

Skin fibrosis in systemic sclerosis (SSc) is accompanied by attrition of dermal white adipose tissue (dWAT) and reduced levels of circulating adiponectin. Since adiponectin has potent regulatory effects on fibroblasts, we sought to assess adiponectin signaling in SSc skin biopsies, and evaluate fibr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Marangoni, Roberta G., Masui, Yuri, Fang, Feng, Korman, Benjamin, Lord, Gabriel, Lee, Junghwa, Lakota, Katja, Wei, Jun, Scherer, Philipp E., Otvos, Laszlo, Yamauchi, Toshimasa, Kubota, Naoto, Kadowaki, Takashi, Asano, Yoshihide, Sato, Shinichi, Tourtellotte, Warren G., Varga, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493638/
https://ncbi.nlm.nih.gov/pubmed/28667272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04162-1
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