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Molecular docking studies on thirteen fluoroquinolines with human topoisomerase II a and b

DNA relaxation is an important step in DNA replication. DNA topoisomerases play a major role in DNA relaxation. Hence these enzymes are important targets for cancer drugs. DNA topoisomerase inhibitors bind to the transient enzyme–DNA complex and inhibit DNA replication. Various inhibitors of topoiso...

詳細記述

保存先:
書誌詳細
出版年:In Silico Pharmacol
主要な著者: Jadhav, Ashwini Khanderao, Karuppayil, Sankunny Mohan
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493602/
https://ncbi.nlm.nih.gov/pubmed/28667488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-017-0024-2
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