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Molecular docking studies on thirteen fluoroquinolines with human topoisomerase II a and b
DNA relaxation is an important step in DNA replication. DNA topoisomerases play a major role in DNA relaxation. Hence these enzymes are important targets for cancer drugs. DNA topoisomerase inhibitors bind to the transient enzyme–DNA complex and inhibit DNA replication. Various inhibitors of topoiso...
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| 出版年: | In Silico Pharmacol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Berlin Heidelberg
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493602/ https://ncbi.nlm.nih.gov/pubmed/28667488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-017-0024-2 |
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