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Molecular docking studies on thirteen fluoroquinolines with human topoisomerase II a and b
DNA relaxation is an important step in DNA replication. DNA topoisomerases play a major role in DNA relaxation. Hence these enzymes are important targets for cancer drugs. DNA topoisomerase inhibitors bind to the transient enzyme–DNA complex and inhibit DNA replication. Various inhibitors of topoiso...
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| Publicado no: | In Silico Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493602/ https://ncbi.nlm.nih.gov/pubmed/28667488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-017-0024-2 |
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