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Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish

Macrophages are known to interact with endothelial cells during developmental and pathological angiogenesis but the molecular mechanisms modulating these interactions remain unclear. Here, we show a role for the Hif-1α transcription factor in this cellular communication. We generated hif-1aa;hif-1ab...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gerri, Claudia, Marín-Juez, Rubén, Marass, Michele, Marks, Alora, Maischein, Hans-Martin, Stainier, Didier Y R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493593/
https://ncbi.nlm.nih.gov/pubmed/28524872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15492
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