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The Association Between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer's Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of Aging

BACKGROUND: Cellular and animal studies demonstrated relationships between sphingolipid metabolism and Alzheimer's disease (AD) pathology. High blood ceramide levels have been shown to predict cognitive impairment and AD, but these studies had small sample sizes and did not assess differences i...

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Détails bibliographiques
Publié dans:J Alzheimers Dis
Auteurs principaux: Mielke, Michelle M., Haughey, Norman J., Han, Dingfen, An, Yang, Bandaru, Veera Venkata Ratnam, Lyketsos, Constantine G., Ferrucci, Luigi, Resnick, Susan M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493514/
https://ncbi.nlm.nih.gov/pubmed/28035934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160925
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