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The Association Between Plasma Ceramides and Sphingomyelins and Risk of Alzheimer's Disease Differs by Sex and APOE in the Baltimore Longitudinal Study of Aging

BACKGROUND: Cellular and animal studies demonstrated relationships between sphingolipid metabolism and Alzheimer's disease (AD) pathology. High blood ceramide levels have been shown to predict cognitive impairment and AD, but these studies had small sample sizes and did not assess differences i...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Mielke, Michelle M., Haughey, Norman J., Han, Dingfen, An, Yang, Bandaru, Veera Venkata Ratnam, Lyketsos, Constantine G., Ferrucci, Luigi, Resnick, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493514/
https://ncbi.nlm.nih.gov/pubmed/28035934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160925
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