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Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

While there are myriad mechanisms of primary and acquired resistance to conventional and next-generation hormonal therapies in prostate cancer, the potential role of androgen receptor splice variants (AR-Vs) has recently gained momentum. AR-Vs are abnormally truncated isoforms of the androgen recept...

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Detalles Bibliográficos
Publicado en:Prostate Cancer Prostatic Dis
Main Authors: Antonarakis, ES, Armstrong, AJ, Dehm, SM, Luo, J
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493501/
https://ncbi.nlm.nih.gov/pubmed/27184811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pcan.2016.17
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