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Androgen Receptor Variant–Driven Prostate Cancer II: Advances in Laboratory Investigations

BACKGROUND: The androgen receptor (AR) is a key prostate cancer drug target. Suppression of AR signaling mediated by the full-length AR (AR-FL) is the therapeutic goal of all existing AR-directed therapies. AR-targeting agents impart therapeutic benefit, but lead to AR aberrations that underlie dise...

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Bibliografiske detaljer
Udgivet i:Prostate Cancer Prostatic Dis
Main Authors: Lu, Changxue, Brown, Landon, Antonarakis, Emmanuel S., Armstrong, Andrew J., Luo, Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725416/
https://ncbi.nlm.nih.gov/pubmed/32139878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-020-0217-3
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