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Re-evaluation of SNP heritability in complex human traits

SNP heritability, the proportion of phenotypic variance explained by SNPs, has been reported for many hundreds of traits. Its estimation requires strong prior assumptions about the distribution of heritability across the genome, but the assumptions in current use have not been thoroughly tested. By...

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Vydáno v:Nat Genet
Hlavní autoři: Speed, Doug, Cai, Na, Johnson, Michael R., Nejentsev, Sergey, Balding, David J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493198/
https://ncbi.nlm.nih.gov/pubmed/28530675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3865
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