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Universal Biotin—PEG-Linked Gold Nanoparticle Probes for the Simultaneous Detection of Nucleic Acids and Proteins

Novel biotin—polyethylene glycol (biotin—PEG) gold nanoparticle probes have been synthesized and used as universal constructs for the detection of protein (prostate-specific antigen, PSA) and nucleic acid targets (microRNAs) from a single sample. Microarray assays based upon these probes enabled sen...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: Scott, Alexander W., Garimella, Viswanadham, Calabrese, Colin M., Mirkin, Chad A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493151/
https://ncbi.nlm.nih.gov/pubmed/27740740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00529
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