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Homogeneous detection of unamplified genomic DNA sequences based on colorimetric scatter of gold nanoparticle probes

Nucleic acid diagnostics is dominated by fluorescence-based assays that use complex and expensive enzyme-based target or signal-amplification procedures1–6. Many clinical diagnostic applications will require simpler, inexpensive assays that can be done in a screening mode. We have developed a ‘spot-...

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Detalhes bibliográficos
Main Authors: Storhoff, James J, Lucas, Adam D, Garimella, Viswanadham, Bao, Y Paul, Müller, Uwe R
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201475/
https://ncbi.nlm.nih.gov/pubmed/15170215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt977
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