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Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles
We find that single- and double-stranded oligonucleotides have different propensities to adsorb on gold nanoparticles in colloidal solution. We use this observation to design a hybridization assay based on color changes associated with gold aggregation. Because the underlying adsorption mechanism is...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521116/ https://ncbi.nlm.nih.gov/pubmed/15381774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406115101 |
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