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Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles

We find that single- and double-stranded oligonucleotides have different propensities to adsorb on gold nanoparticles in colloidal solution. We use this observation to design a hybridization assay based on color changes associated with gold aggregation. Because the underlying adsorption mechanism is...

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Bibliografiset tiedot
Päätekijät: Li, Huixiang, Rothberg, Lewis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC521116/
https://ncbi.nlm.nih.gov/pubmed/15381774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406115101
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