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Colorimetric detection of DNA sequences based on electrostatic interactions with unmodified gold nanoparticles
We find that single- and double-stranded oligonucleotides have different propensities to adsorb on gold nanoparticles in colloidal solution. We use this observation to design a hybridization assay based on color changes associated with gold aggregation. Because the underlying adsorption mechanism is...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15381774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406115101 |
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