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Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer

The nucleosome core particle, the basic repeated structure in chromatin fibers, consists of an octamer of eight core histone molecules, organized as dimers (H2A/H2B) and tetramers [(H3/H4)(2)] around which DNA wraps tightly in almost two left-handed turns. The nucleosome has to undergo certain confo...

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Detalhes bibliográficos
Main Authors: Tomschik, Miroslav, Zheng, Haocheng, van Holde, Ken, Zlatanova, Jordanka, Leuba, Sanford H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549292/
https://ncbi.nlm.nih.gov/pubmed/15728351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500189102
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