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Linker histones affect patterns of digestion of supercoiled plasmids by single-strand-specific nucleases.

The effect of histone H1 binding on the cleavage of superhelical plasmids by single-strand-specific nucleases was investigated. Mapping of P1 cleavage sites in pBR322, achieved by EcoRI digestion after the original P1 attack, showed an intriguing phenomenon: preexisting susceptible sites became "pro...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Ivanchenko, M, Zlatanova, J, Varga-Weisz, P, Hassan, A, van Holde, K
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1996
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38918/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.6970
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