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Immunogenicity in humans of an edible vaccine for hepatitis B

A double-blind placebo-controlled clinical trial evaluated the immunogenicity of hepatitis B surface antigen (HBsAg) expressed in potatoes and delivered orally to previously vaccinated individuals. The potatoes accumulated HBsAg at ≈8.5 μg/g of potato tuber, and doses of 100 g of tuber were administ...

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Autori principali: Thanavala, Yasmin, Mahoney, Martin, Pal, Sribani, Scott, Adrienne, Richter, Liz, Natarajan, Nachimuthu, Goodwin, Patti, Arntzen, Charles J., Mason, Hugh S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC549291/
https://ncbi.nlm.nih.gov/pubmed/15728371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409899102
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