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Immunogenicity in humans of an edible vaccine for hepatitis B
A double-blind placebo-controlled clinical trial evaluated the immunogenicity of hepatitis B surface antigen (HBsAg) expressed in potatoes and delivered orally to previously vaccinated individuals. The potatoes accumulated HBsAg at ≈8.5 μg/g of potato tuber, and doses of 100 g of tuber were administ...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549291/ https://ncbi.nlm.nih.gov/pubmed/15728371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409899102 |
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