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Amphetamine induces dopamine efflux through a dopamine transporter channel

Drugs of abuse, including cocaine, amphetamine (AMPH), and heroin, elevate extracellular dopamine (DA) levels in the brain, thereby altering the activity/plasticity of reward circuits and precipitating addiction. The physiological release of DA occurs through the calcium-dependent fusion of a synapt...

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Autors principals: Kahlig, Kristopher M., Binda, Francesca, Khoshbouei, Habibeh, Blakely, Randy D., McMahon, Douglas G., Javitch, Jonathan A., Galli, Aurelio
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549289/
https://ncbi.nlm.nih.gov/pubmed/15728379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407737102
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