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Amphetamine induces dopamine efflux through a dopamine transporter channel

Drugs of abuse, including cocaine, amphetamine (AMPH), and heroin, elevate extracellular dopamine (DA) levels in the brain, thereby altering the activity/plasticity of reward circuits and precipitating addiction. The physiological release of DA occurs through the calcium-dependent fusion of a synapt...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kahlig, Kristopher M., Binda, Francesca, Khoshbouei, Habibeh, Blakely, Randy D., McMahon, Douglas G., Javitch, Jonathan A., Galli, Aurelio
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15728379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407737102
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