Potential Role of Patients’ CYP3A-Status in Clozapine Pharmacokinetics

BACKGROUND: The atypical antipsychotic clozapine is effective in treatment-resistant schizophrenia; however, the success or failure of clozapine therapy is substantially affected by the variables that impact the clozapine blood concentration. Thus, elucidating the inter-individual differences in clo...

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Bibliographic Details
Published in:Int J Neuropsychopharmacol
Main Authors: Tóth, Katalin, Csukly, Gábor, Sirok, Dávid, Belic, Ales, Kiss, Ádám, Háfra, Edit, Déri, Máté, Menus, Ádám, Bitter, István, Monostory, Katalin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Regular Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492788/
https://ncbi.nlm.nih.gov/pubmed/28340122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx019
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