Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain

Chronic neuroinflammation, which is primarily mediated by microglia, plays an essential role in aging and neurodegeneration. It is still unclear whether this microglia-induced neuroinflammation occurs globally or is confined to distinct brain regions. In this study, we investigated microglia activit...

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Dettagli Bibliografici
Pubblicato in:Front Mol Neurosci
Autori principali: Raj, Divya, Yin, Zhuoran, Breur, Marjolein, Doorduin, Janine, Holtman, Inge R., Olah, Marta, Mantingh-Otter, Ietje J., Van Dam, Debby, De Deyn, Peter P., den Dunnen, Wilfred, Eggen, Bart J. L., Amor, Sandra, Boddeke, Erik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492660/
https://ncbi.nlm.nih.gov/pubmed/28713239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00206
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