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CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development

The midbrain-hindbrain boundary (MHB) acts as an organizer and controls the fate of neighboring cells to develop into either mesencephalic (midbrain) or metencephalic (hindbrain) cells by secreting signaling molecules like Wnt1 and Fgf8. The zebrafish is an excellent vertebrate model for studying MH...

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Bibliografske podrobnosti
izdano v:Front Neuroanat
Main Authors: Kesavan, Gokul, Chekuru, Avinash, Machate, Anja, Brand, Michael
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492657/
https://ncbi.nlm.nih.gov/pubmed/28713249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00052
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