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CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development

The midbrain-hindbrain boundary (MHB) acts as an organizer and controls the fate of neighboring cells to develop into either mesencephalic (midbrain) or metencephalic (hindbrain) cells by secreting signaling molecules like Wnt1 and Fgf8. The zebrafish is an excellent vertebrate model for studying MH...

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Detalhes bibliográficos
Publicado no:Front Neuroanat
Main Authors: Kesavan, Gokul, Chekuru, Avinash, Machate, Anja, Brand, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492657/
https://ncbi.nlm.nih.gov/pubmed/28713249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2017.00052
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