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Deletion of the Multiple-Drug Efflux Pump AcrAB in Escherichia coli Prolongs the Postantibiotic Effect
The mechanism of the postantibiotic effect (PAE) was examined in Escherichia coli. Drugs exhibited longer-lasting PAEs in an acrAB mutant, suggesting that intracellular drug concentrations influence the duration of the PAE. With specific assays for tetracycline and erythromycin, a direct link betwee...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549255/ https://ncbi.nlm.nih.gov/pubmed/15728929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1206-1208.2005 |
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