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Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis

More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil burden which persists within the airways; nor why...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Infect Microbiol
Prif Awduron: Marteyn, Benoît S., Burgel, Pierre-Régis, Meijer, Laurent, Witko-Sarsat, Véronique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492487/
https://ncbi.nlm.nih.gov/pubmed/28713772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00243
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