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Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis

More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and the tremendous neutrophil burden which persists within the airways; nor why...

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Détails bibliographiques
Publié dans:Front Cell Infect Microbiol
Auteurs principaux: Marteyn, Benoît S., Burgel, Pierre-Régis, Meijer, Laurent, Witko-Sarsat, Véronique
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492487/
https://ncbi.nlm.nih.gov/pubmed/28713772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00243
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