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Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

BACKGROUND: The tauGFP reporter fusion protein is produced nearly ubiquitously by the TgTP6.3 transgene in TP6.3 mice and its localisation to microtubules offers some advantages over soluble GFP as a lineage marker. However, TgTP6.3 (Tg/Tg) homozygotes are not viable and TgTP6.3 (Tg/−) hemizygotes a...

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Detalhes bibliográficos
Publicado no:BMC Dev Biol
Main Authors: Sharp, Linda, Pratt, Thomas, MacKay, Gillian E., Keighren, Margaret A., Flockhart, Jean H., Chandler, Emma J., Price, David J., Mason, John O., West, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492368/
https://ncbi.nlm.nih.gov/pubmed/28662681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-017-0149-x
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