Mechanism of Action of T-705 against Influenza Virus

T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo. In a time-of-addition study, it was indicated that T-705 targeted an early to middle stage of the viral replication cycle but had no effect on the adsorption or release stage....

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Autores principales: Furuta, Yousuke, Takahashi, Kazumi, Kuno-Maekawa, Masako, Sangawa, Hidehiro, Uehara, Sayuri, Kozaki, Kyo, Nomura, Nobuhiko, Egawa, Hiroyuki, Shiraki, Kimiyasu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC549233/
https://ncbi.nlm.nih.gov/pubmed/15728892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.981-986.2005
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