Impaired fracture healing with high non-union rates remains irreversible after traumatic brain injury in leptin-deficient mice

Patients with traumatic brain injury (TBI) and long-bone fractures can show increased callus formation. This effect has already been reproduced in wild-type (wt) mice. However, the mechanisms remain poorly understood. Leptin is significantly increased following TBI, while its role in bone healing re...

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Vydáno v:J Musculoskelet Neuronal Interact
Hlavní autoři: Graef, F., Seemann, R., Garbe, A., Schmidt-Bleek, K., Schaser, K-D., Keller, J., Duda, G., Tsitsilonis, S.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Society of Musculoskeletal and Neuronal Interactions 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492322/
https://ncbi.nlm.nih.gov/pubmed/28574414
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