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Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptides
Gemcitabine (Gem) is used as a single agent or in combination with other anticancer agents to treat many types of solid tumors. However, it has many limitations such as a short plasma half-life, dose-limiting toxicities and drug resistance. Cell-penetrating peptides (CPPs) are short peptides which m...
Enregistré dans:
| Publié dans: | EXCLI J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Leibniz Research Centre for Working Environment and Human Factors
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491906/ https://ncbi.nlm.nih.gov/pubmed/28694765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2017-249 |
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