15-Deoxy-Delta-12,14-Prostaglandin J(2) Inhibits Lung Inflammation and Remodeling in Distinct Murine Models of Asthma

15-deoxy-Δ-12,14-prostaglandin J(2) (15d-PGJ(2)) has been described as an anti-inflammatory lipid mediator in several in vitro and in vivo studies, but its effect on allergic pulmonary inflammation remains elusive. The aim of this study was to investigate the therapeutic potential of 15d-PGJ(2) base...

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Udgivet i:Front Immunol
Main Authors: Coutinho, Diego S., Anjos-Valotta, Edna A., do Nascimento, Caio V. M. F., Pires, Ana Lucia A., Napimoga, Marcelo H., Carvalho, Vinícius F., Torres, Rafael C., e Silva, Patrícia M. R., Martins, Marco A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491902/
https://ncbi.nlm.nih.gov/pubmed/28713373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00740
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