15-Deoxy-Delta-12,14-Prostaglandin J(2) Inhibits Lung Inflammation and Remodeling in Distinct Murine Models of Asthma

15-deoxy-Δ-12,14-prostaglandin J(2) (15d-PGJ(2)) has been described as an anti-inflammatory lipid mediator in several in vitro and in vivo studies, but its effect on allergic pulmonary inflammation remains elusive. The aim of this study was to investigate the therapeutic potential of 15d-PGJ(2) base...

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Publicat a:Front Immunol
Autors principals: Coutinho, Diego S., Anjos-Valotta, Edna A., do Nascimento, Caio V. M. F., Pires, Ana Lucia A., Napimoga, Marcelo H., Carvalho, Vinícius F., Torres, Rafael C., e Silva, Patrícia M. R., Martins, Marco A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491902/
https://ncbi.nlm.nih.gov/pubmed/28713373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00740
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