Insights into the catalysis of a lysine-tryptophan bond in bacterial peptides by a SPASM domain radical S-adenosylmethionine (SAM) peptide cyclase

Radical S-adenosylmethionine (SAM) enzymes are emerging as a major superfamily of biological catalysts involved in the biosynthesis of the broad family of bioactive peptides called ribosomally synthesized and post-translationally modified peptides (RiPPs). These enzymes have been shown to catalyze u...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Benjdia, Alhosna, Decamps, Laure, Guillot, Alain, Kubiak, Xavier, Ruffié, Pauline, Sandström, Corine, Berteau, Olivier
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491770/
https://ncbi.nlm.nih.gov/pubmed/28476884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783464
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