Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation

We recently proved that exosomes engineered in vitro to deliver high amounts of HPV E7 upon fusion with the Nef(mut) exosome-anchoring protein elicit an efficient anti-E7 cytotoxic T lymphocyte immune response. However, in view of a potential clinic application of this finding, our exosome-based imm...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Di Bonito, Paola, Chiozzini, Chiara, Arenaccio, Claudia, Anticoli, Simona, Manfredi, Francesco, Olivetta, Eleonora, Ferrantelli, Flavia, Falcone, Emiliana, Ruggieri, Anna, Federico, Maurizio
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491702/
https://ncbi.nlm.nih.gov/pubmed/28694699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S131309
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