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The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity
The degeneration of dopaminergic neurons during Parkinson’s disease (PD) is intimately linked to malfunction of α-synuclein (αSyn), the main component of the proteinaceous intracellular inclusions characteristic for this pathology. The cytotoxicity of αSyn has been attributed to disturbances in seve...
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| 出版年: | Front Mol Neurosci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491553/ https://ncbi.nlm.nih.gov/pubmed/28713240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00207 |
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