Persistence of Activated and Adaptive-Like NK Cells in HIV(+) Individuals despite 2 Years of Suppressive Combination Antiretroviral Therapy

Innate immune dysfunction persists in HIV(+) individuals despite effective combination antiretroviral therapy (cART). We recently demonstrated that an adaptive-like CD56(dim) NK cell population lacking the signal transducing protein FcRγ is expanded in HIV(+) individuals. Here, we analyzed a cohort...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Hearps, Anna C., Agius, Paul A., Zhou, Jingling, Brunt, Samantha, Chachage, Mkunde, Angelovich, Thomas A., Cameron, Paul U., Giles, Michelle, Price, Patricia, Elliott, Julian, Jaworowski, Anthony
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491541/
https://ncbi.nlm.nih.gov/pubmed/28713370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00731
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