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Decreased NK Cell FcRγ in HIV-1 Infected Individuals Receiving Combination Antiretroviral Therapy: a Cross Sectional Study

BACKGROUND: FcRγ is an immunoreceptor tyrosine-based activation motif (ITAM)-signalling protein essential for immunoreceptor signaling and monocyte, macrophage and NK cell function. Previous study from our laboratory showed that FcRγ is down-regulated in HIV-infected macrophages in vitro. FcRγ expre...

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Autors principals: Leeansyah, Edwin, Zhou, Jingling, Paukovics, Geza, Lewin, Sharon R., Crowe, Suzanne M., Jaworowski, Anthony
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835768/
https://ncbi.nlm.nih.gov/pubmed/20224795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009643
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