Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques

Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV infections. We recently isolated a panel of potent...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Broeckel, Rebecca, Fox, Julie M., Haese, Nicole, Kreklywich, Craig N., Sukulpovi-Petty, Soila, Legasse, Alfred, Smith, Patricia P., Denton, Michael, Corvey, Carsten, Krishnan, Shiv, Colgin, Lois M. A., Ducore, Rebecca M., Lewis, Anne D., Axthelm, Michael K., Mandron, Marie, Cortez, Pierre, Rothblatt, Jonathan, Rao, Ercole, Focken, Ingo, Carter, Kara, Sapparapau, Gopal, Crowe, James E., Diamond, Michael S., Streblow, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491320/
https://ncbi.nlm.nih.gov/pubmed/28628616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005637
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