IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis

IL-36 cytokines are proinflammatory and have an important role in innate and adaptive immunity, but the role of IL-36 signaling in renal tubulointerstitial lesions (TILs), a major prognostic feature of renal inflammation and fibrosis, remains undetermined. In this study, increased IL-36α expression...

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Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Chi, Hsi-Hua, Hua, Kuo-Feng, Lin, Yu-Chuan, Chu, Ching-Liang, Hsieh, Chih-Yu, Hsu, Yu-Juei, Ka, Shuk-Man, Tsai, Yu-Ling, Liu, Feng-Cheng, Chen, Ann
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2017
Ämnen:
Basic Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491282/
https://ncbi.nlm.nih.gov/pubmed/28179433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016080840
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