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Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy

Doxorubicin is a potent chemotherapeutic agent that is widely-used to treat a variety of cancers but causes acute and chronic cardiac injury, severely limiting its use. Clinically, the acute side effects of doxorubicin are mostly manageable, whereas the delayed consequences can lead to life-threaten...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Piotrowska, Izabela, Isalan, Mark, Mielcarek, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491252/
https://ncbi.nlm.nih.gov/pubmed/28662206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180571
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