The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.

To investigate mechanisms responsible for positive and negative transcriptional control, we have utilized two types of promoters that are differentially regulated by thyroid hormone (T3) receptors. Promoters containing the palindromic T3 response element TCAGGTCA TGACCTGA are positively regulated by...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Holloway, J M, Glass, C K, Adler, S, Nelson, C A, Rosenfeld, M G
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC54912/
https://ncbi.nlm.nih.gov/pubmed/2236029
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