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CARMIL family proteins as multidomain regulators of actin-based motility

CARMILs are large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major capper of actin filament barbed ends in cells. CARMILs bind directly to CP and induce a conformational change that allosterically decreases but does not abolish its actin-capping activity...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Stark, Benjamin C., Lanier, M. Hunter, Cooper, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491179/
https://ncbi.nlm.nih.gov/pubmed/28663287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0019
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