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Detecting similar binding pockets to enable systems polypharmacology
In the era of systems biology, multi-target pharmacological strategies hold promise for tackling disease-related networks. In this regard, drug promiscuity may be leveraged to interfere with multiple receptors: the so-called polypharmacology of drugs can be anticipated by analyzing the similarity of...
שמור ב:
| הוצא לאור ב: | PLoS Comput Biol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490940/ https://ncbi.nlm.nih.gov/pubmed/28662117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005522 |
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