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Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase

Allosteric inhibitors of hepatitis C virus (HCV) non-structural protein 5B (NS5B) polymerase are effective for treatment of genotype 1, although their mode of action and potential to inhibit other isolates and genotypes are not well established. We have used biophysical techniques and a novel biosen...

詳細記述

保存先:
書誌詳細
出版年:Viruses
主要な著者: Abdurakhmanov, Eldar, Øie Solbak, Sara, Danielson, U. Helena
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490826/
https://ncbi.nlm.nih.gov/pubmed/28621755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9060151
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