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Securing stem cell identity by asymmetrically amplifying Notch activity
Stem cells self-renew and produce progenitors with limited proliferative potential. Reporting in Developmental Cell, Liu et al. (2017) demonstrate that in some neural stem cells, Notch activity is asymmetrically amplified by a positive feedback loop with the Super Elongation transcription Complex (S...
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| Vydáno v: | Dev Cell |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490801/ https://ncbi.nlm.nih.gov/pubmed/28350981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.03.010 |
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