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RASA1 regulates the function of lymphatic vessel valves in mice

Capillary malformation–arteriovenous malformation (CM-AVM) is a blood and lymphatic vessel (LV) disorder that is caused by inherited inactivating mutations of the RASA1 gene, which encodes p120 RasGAP (RASA1), a negative regulator of the Ras small GTP-binding protein. How RASA1 mutations lead to the...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lapinski, Philip E., Lubeck, Beth A., Chen, Di, Doosti, Abbas, Zawieja, Scott D., Davis, Michael J., King, Philip D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490778/
https://ncbi.nlm.nih.gov/pubmed/28530642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89607
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