RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice

RASA1 (also known as p120 RasGAP) is a Ras GTPase–activating protein that functions as a regulator of blood vessel growth in adult mice and humans. In humans, RASA1 mutations cause capillary malformation–arteriovenous malformation (CM-AVM); whether it also functions as a regulator of the lymphatic v...

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Autors principals: Lapinski, Philip E., Kwon, Sunkuk, Lubeck, Beth A., Wilkinson, John E., Srinivasan, R. Sathish, Sevick-Muraca, Eva, King, Philip D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266774/
https://ncbi.nlm.nih.gov/pubmed/22232212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46116
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