Global expression changes resulting from loss of telomeric DNA in fission yeast

BACKGROUND: Schizosaccharomyces pombe cells lacking the catalytic subunit of telomerase (encoded by trt1(+)) lose telomeric DNA and enter crisis, but rare survivors arise with either circular or linear chromosomes. Survivors with linear chromosomes have normal growth rates and morphology, but those...

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Bibliografiske detaljer
Main Authors: Mandell, Jeffrey G, Bähler, Jürg, Volpe, Thomas A, Martienssen, Robert A, Cech, Thomas R
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549061/
https://ncbi.nlm.nih.gov/pubmed/15642092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-6-1-r1
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