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Specific replication origins promote DNA amplification in fission yeast
To ensure equal replication of the genome in every eukaryotic cell cycle, replication origins fire only once each S phase and do not fire after passive replication. Failure in these controls can lead to local amplification, contributing to genome instability and the development of cancer. To identif...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Company of Biologists
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931602/ https://ncbi.nlm.nih.gov/pubmed/20736315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.067470 |
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