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Specific replication origins promote DNA amplification in fission yeast

To ensure equal replication of the genome in every eukaryotic cell cycle, replication origins fire only once each S phase and do not fire after passive replication. Failure in these controls can lead to local amplification, contributing to genome instability and the development of cancer. To identif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kiang, Lee, Heichinger, Christian, Watt, Stephen, Bähler, Jürg, Nurse, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931602/
https://ncbi.nlm.nih.gov/pubmed/20736315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.067470
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