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Ligand-directed dibromophenyl benzoate chemistry for rapid and selective acylation of intracellular natural proteins
A rapid and selective ligand-directed chemical reaction was developed for the acylation of proteins in living cells on the basis of ligand-directed chemistry. By fine tuning the reactivity and stability of the phenyl ester derivatives, we successfully identified ortho-dibromophenyl benzoate as the o...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490417/ https://ncbi.nlm.nih.gov/pubmed/28706692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00190k |
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